Duke Research in Engineering and Surgical Technologies (Duke REST) is a new collaboration between the Department of Surgery and the Pratt School of Engineering at Duke University to study, critique, and develop novel technical capabilities for use in the operating room, emergency room, and clinic. Hospitals continue to introduce novel technologies for physicians, physician assistants, and nurses to use in their daily responsibilities. Duke REST focuses research efforts on evaluating and developing such new medical technologies, researching clinical outcomes, and discovering objective metrics for evaluating physician proficiency. This collaboration between Surgery and Engineering brings together expert clinicians, researchers, and data analysts to solve complex problems that bridge the gap between medicine and engineering. Duke REST takes an agnostic approach to private industry by partnering with companies and organizations to evaluate new technologies via rigorous usability, ergonomics, and adaptability testing. Such research goals have the potential to lead to better patient outcomes and more cost effective treatments.